- Ryuhi Kanehara, Yuki Oinuma, Hayato Maeda, Kazuaki Tanaka, Masaru Hashimoto
Triantaspirols A–C and Paraphaeolactone Cs from Paraphaeosphaeria sp. KT4192:
Sensitivity of CP3 in Distinguishing Close NMR Signals
J. Nat. Prod. 2024, accepted
- 橋本勝,: 天然物の不思議な構造に魅せられて, 有機合成化学協会誌, 2024, 82, 9, 922-925.
- 橋本勝: 計算機化学を利用した有機化合物の構造決定 密度汎関数化学シフト計算の進展, 月刊化学, 2024, 79, 9, 70-71.
- Taichiro Tokizaki, Ryuhi Kanehara, Hayato Maeda, Kazuaki Tanaka, and Masaru
Hashimoto
Highly Functionalized Spirobisnaphthalenes from Roussoella sp. KT4147
J. Nat. Prod. 2024, 87, 1798-1807.
- Shunta Kobayashi, Nurcahyo Iman Prakoso, Xin Zheng, Shin-ichiro Noro, Masaru
Hashimoto, Tatsuya Morozumi, and Taiki Umezawa
Synthesis and Conformational Analysis of α,β-Dichlorocarbonyl Compounds
Eur. J. Org. Chem., 2024, 27, e202400489..
- H. Arita, R. Tanaka, S. Kikukawa, T. Tomizawa, H. Sakata, M. Funada, K.
Tomiyama, M. Hashimoto, T. Tasaka, H. Tabata, K. Nakamura, K. Makino, T.
Oshitari, H. Natsugari, H. Takahashi: J. Med. Chem. 2024, 67, 10447-10463.l.
Fentanyl-Type Antagonist of the μ-Opioid Receptor: Important Role of Axial
Chirality in the Active Conformation
J. Med. Chem. 2024, 67, 10447-10463.
- K. Hashimoto, H. Maeda, M. Hashimoto,
Stereoselective Preparation of the Tricyclic Hexa-substituted Spirocyclopropane Core of Cyclohelminthol X
Org. Lett. 2024, 26, 5873-5876.
- Y. Horie, M. Uchikata, S. Ueda, G. Yamahira, M. Hashimoto, K. Sakamoto,
H. Ito, S. Hamada
In vitro synthesis of oryzamutaic acid H using recombinant L-lysineε-dehydrogenase
from Agrobacterium tumefaciens
J. Biotech. 2024, 385 , 42-48.
- Y. Oinuma, R. Kanehara, H. Maeda, T. Nishikawa, K. Konno, K. Tanaka, M Hashimoto
Isolation of Paraphaeoketones: A Plausible Biosynthetic Explanation for
Paraphaeolactones via a Benzilic Acid Rearrangement Rather than a Favorskii
Rearrangement
J. Nat. Prod. 2024, 87 (4), 1159-1170.
- K. Ujiie, C. Tanaka, M. Arai, M. Hashimoto, Y. Yoshida, T. Kawano, S. Tamura
Proposal for Structure Revision of Pinofuranoxin A through Total Syntheses of Stereoisomers
J. Nat.l Med, 2024, 78, 608-617.
- J. Wu, K. Uchida, A. Yoshikawa, M. Hashimoto, M. Kondo, K. Nihei, M. Ishii, J-H. Choi, Y. Miwa, C. Shoda, D. Lee, A. Nakai, T. Kurihara, C. N. D’Alessandro-Gabazza, M. Toda, T. Yasuma, E. C. Gabazza, H. Hirai, H. Kawagishi
"Fruiting Liquid” of Mushroom-Forming Fungi, A Novel Source of Bioactive Compounds – Fruiting-Body Inducer and HIF and Axl Inhibitors
J. Agr. Food Chem, 2023, 71, 13338-13345
- K. Hashimoto, K. Kimura, K. Ishida, E. Morita, K. Tanaka. M. Hashimoto
HIV-1 Integrase Inhibitor, Dihydroobionin B, and the Investigation of Its
Extraordinary Specific Rotation
J. Nat. Prod. 2023, 2139–2144
- R. Kanehara, Y. Oinuma, H. Maeda, M. Okazaki, K. Konno, K. Tanaka, M. Hashimoto
Pseudo-Enantiomeric Paraphaeolactones and Their Biosynthetic Derivatives
from Paraphaeosphaeria sp. KT4192: A Proposition of a Favorskii Rearrangement for Their Biosynthesis
J. Nat. Prod. 2023, 86, 1832-1843.
- J. Wu, Y. Kamiishi, K. Shimozaki, M. Kondo, M. Hashimoto, J. Choi, C. N
D’Alessandro-Gabazza, M. Toda, T. Yasuma, E. C Gabazza, H. Hirai, H. Kawagishi
Novel cyclopropyl compounds, cyclopropylvirgines A to G, from the fruiting
bodies of Amanita virgineoides
Bull. Chem. Soc. Jpn. 2023, 96 (6), 503-509
- R. Kanehara, K. Tanaka, T. Yamada, H. Koshino and M. Hashimoto
Termination of the Chirality Confusion of Peribysins
Bull. Chem. Soc. Jpn. 2023, 96 (4), 318-320 (selected paper)
- S. Miura, K. Ishida, K. Tanaka, E. Morita and M. Hashimoto
Integrasone Derivatives Isolated from Lepteutypa sp. KT4162 and Their Anti-HIV-1
Integrase Activity
J. Nat. Prod. 2023, 86(4), 1019-1024
- R. Kanehara, A. Tonouchi, K. Konno, H.i Koshino, M. Hashimoto,*
Isolation of cyclohumulanoids from Daedaleopsis tricolor and their biosynthesis based on in silico simulations
Tetrahedron, 2022, 92, 132251.
- Naoaki Kurisawa, Arihiro Iwasaki, Kazuya Teranuma, Shingo Dan, Chikashi
Toyoshima, Masaru Hashimoto, Kiyotake Suenaga
Structural Determination, Total Synthesis, and Biological Activity of Iezoside,
a Highly Potent Ca2+-ATPase Inhibitor from the Marine Cyanobacterium Leptochromothrix
valpauliae
J. Am. Chem. Soc. 2022, 144 (24), 11019–11032.
- Ayane Hayasaka, Kazuki Hashimoto, Katsuhiro Konno, Kazuaki Tanaka, Masaru Hashimoto
Isolation, Identification, and DFT-based Conformational Analysis of Sesquikarahanadienone and its Congeners from Freshwater Dothideomycetes Neohelicascus aquaticus KT4120
Bull. Chem. Soc. Jpn. 2022, 95 (5), 833-845
BCSJ Award article
- Takino, Junya, Kotani, Akari, Ozaki, Taro, Peng, Wenquan, Yu, Jie, Guo,
Yian, Mochizuki, Susumu, Akimitsu, Kazuya, Hashimoto, Masaru, Ye, Tao,
Minami, Atsushi, Oikawa, Hideaki
Biochemistry-Guided Prediction of the Absolute Configuration of Fungal
Reduced Polyketides
Angewandte Chemie International Edition, 2021, 60, 43, 23403-23411
- Ryuhi Kanehara, Akio Tonouchi, Katsuhiro Konno, and Masaru Hashimoto
Cyclohumulanoid Sesquiterpenes from the Culture Broth of the Basidiomycetous
Fungus Daedaleopsis tricolor
Molecules, 2021, 26 (14), 4364..
- Ayane Hayasaka, Kazuaki Tanaka, and Masaru Hashimoto
Isolation and Structural Elucidation of Novel Fusicoccan Dehydroxypericonicin
A from Roussoella sp.
Biosci. Biotech. Biochem. 2021, 85(8), 1798-1801.
-
Ryuhi Kanehara, Ayane Hayasaka, Kota Inose,
Takeshi Okamura, Satomi Miura, Kazuaki Tanaka, and Masaru Hashimoto
Decaspirones and Palmarumycins from Phaeoseptum sp. KT4106: Chirality Reinvestigation of Palmarumycins CP4a and CP5
Tetrahedron Lett., 2021, 92, 132251
-
Osamu Ishibashi, Mami Nishiyama, Eunsang
Kwon, Masaru Hashimoto, Shigefumi Kuwahara, Masaru Enomoto
Semipinacol rearrangement of a bicyclo [7.2. 0] undecane framework into
a bicyclo [6.3. 0] undecane skeleton: A model study on the biosynthesis
of seiridiasteriscane A
Biosci. Biotech. Biochem. 2021, 85(7), 1621-2627
-
Inose, Kota; Tanaka, Shizuya; Tanaka, Kazuaki; Hashimoto, Masaru,
Cyclohelminthol CPs: Scope and Limitations of Density-functional-theory-based Structural Elucidation of Natural Products
J. Org. Chem., 2021, 86( 2), 1505-1515..
- Wilanfranco C Tayone, Kotaro Ishida, Simon Goto, Janeth C Tayone, Masashi Arakawa, Eiji Morita, Masaru Hashimoto
Anti-Japanese Encephalitis Virus (JEV) Activity of Triterpenes and Flavonoids
from Euphorbia hirta
Philippine Journal of Science 149 (3), 603-613 2020
- M. Matsumoto, S. Miura, A. Tonouchi, Masaru Hashimoto*
DFT-Supported structure determination of gymunomitr-3(15)-en-4b,9b-diol
Tetrahedron, 2020, 76(27), 131301
- Wilanfranco C. Tayone, Mami Nishiyama, Kazuaki Tanaka Masaru Enomoto, and Masaru Hashimoto
DFT Supported Structural Elucidations of Seiridiasteriscane A, Unique 15-nor-Asteriscane
and Novel Pestalotiopsin Congeners from Seiridium sp. KT3957
Tetrahedron, 2020,76, (20), 131197
-
Mami Nishiyama, Wilanfranco C. Tayone, Hayato Maeda, Kazuaki Tanaka, Masaru
Hashimoto
DFT Supported Structural Revision of Seiricardines
Bull. Chem. Soc. Jpn. 2020, 93(6), 768-775.
-
Tetsuya Shiina, Taro Ozaki, Yusuke Matsu, Shota
Nagamine, Chengwei Liu, Masaru Hashimoto, Atsushi Minami, Hideaki Oikawa
Oxidative Ring Contraction by a Multifunctional Dioxygenase Generates the
Core Cycloocatadiene in the Biosynthesis of Fungal Dimeric Anhydride Zopfiellin
Org. Lett., 2020, 22 (5), 1997-2000.
- Uesugi S, Honmura Y, Nishiyama M, Kusakabe K, Tonouchi A, Yamashita T,
Hashimoto M, Kimura K-i.
Identification of neomacrophorins isolated from Trichoderma sp. 1212-03
as proteasome inhibitors.
Bioorg. Med. Chem. 2019, 27, 115161.
- Mami Nishiyama, Akio Tonouchi, Hayato Maeda, and Masaru Hashimoto
DFT calculation-assisted stereo-structural assignment of arundifungin
Chirality, 2020, 32, 17-31
- 橋本勝, 福士江里, Warren Hehre
DFT計算支援による天然物のNMR解析
日本核磁気共鳴学会機関誌、2019, vol10, 31-41.
- Hehre, W. J.; Kuunzinger, P.; Deppmeier, B.; Driessen, A.; Uchida, N.;
Hashimoto, M.; Fukushi, E.; Takata, Y.,
An Efficient Protocol for Accurately Calculating 13C Chemical Shifts of Conformationally Flexible Natural Products: Scope,
Assessment and Limitations.
J. Nat. Prod. 2019 82, 2299-2306.
.
- Kota Inose, Kazuaki Tanaka, Hiroyuki Koshino, Masaru Hashimoto
Cyclopericodiol and Novel Chlorinated Melleins Isolated from Periconia macrospinosa KT3863
Tetrahedron, 2019, 75, 130470
- Takahiro Ugai, Atsushi MInami, Shizuya Tanaka, Raro Ozaki, Chengwei Liu,
Hideyuki Shigemori, Masaru Hashimoto, Hideaki Oikawa
Biosynthetic machinery of 6‐hydroxymellein derivatives leading to cyclohelminthols
and palmaenones
ChemBioChem, accepted publication
- Mami Nishiyama, Hayato Maeda, Akio Tonouchi, and Masaru Hashimoto
Neomacrophorin and Premacrophorin Congeners from Trichoderma sp. 1212-03
Tetrahedron, 2019, 75, 2993-3000.
- Manami Matsumoto, Mami Nishiyama, Hayato Maeda, Akio Tonouchi, Katsuhiro Konno, Masaru Hashimoto
- Kota Inose, Kazuaki Tanaka, Takeshi Yamada, Hiroyuki Koshino, Masaru Hashimoto
- Yoshida, K.; Nagai, N.; Ichikawa, Y.; Goto, M.; Kazuma, K.; Oyama, K.-i.;
Koga, K.; Hashimoto, M.; Iuchi, S.; Takaya, Y.; Kondo, T.,
Structure of two purple pigments, catechiopyranocyanidins A and B from
the seed-coat of the small red bean, Vigna angularis
Scientific Reports 2019, 9, 1484.
- Shiina, T.; Nakagawa, K.; Fujisaki, Y.; Ozaki, T.; Liu, C.; Toyomasu, T.;
Hashimoto, M.; Koshino, H.; Minami, A.; Kawaide, H.; Oikawa, H.
Biosynthetic study of conidiation-inducing factor conidiogenone: heterologous
production and cyclization mechanism of a key bifunctional diterpene synthase.
Biosci. Biotech. Biochem. 2019, 83, 192-201.
- Maeno, M.; Sasaki, K.; Guo, M.; Hashimoto, M.; Shiro, M.; Shibata, N
Synthesis of Chiral Nonracemic α-Difluoromethylthio Compounds with Tetrasubstituted
Stereogenic Centers via a Palladium-Catalyzed Decarboxylative Asymmetric
Allylic Alkylation.
Org. Lett. 2018, 20, 7044-7048.
- 橋本勝
リンゴ果実におけるマイコパラサイト現象の生物有機化学
日本農薬学会誌, 2018, 43, 101-108.
- 橋本 勝
天然物構造決定におけるDFT計算の活用
有機合成化学協会誌 2018, 76, 842-850
- Shizuya Tanaka, Kazuaki Tanaka, Hayato Maeda, and Masaru Hashimoto
Cyclohelminthols Y1-Y4 Metabolites Possessing Two Spirocyclopropanes in their Structure
J. Org. Chem. 2018, 83, 5688-5697
- Manami Matsumoto, Shizuya Tanaka, Akio Tonouchi, and Masaru Hashimoto
12-Deoxyroridin J and 12-Deoxyepiisororidin E from Calcarisporium arbuscular
Tetrahedron Letters, 2018. 59, 1992-1995.
- Manami Matsumoto, Atsushi Ito, Akio Tonouchi, Masaaki Okazaki, Masaru Hashimoto
Stereochemical Correction and Total Structure of Roridin J
Tetrahedron, 2017, 73, 5430-5435.
- Shizuya Tanaka, Yuna Honmura, Shota Uesugi, Eri Fukushi, Kazuaki Tanaka,
Hayato Maeda, Ken-ichi Kimura, Tatsuo Nehira, Masaru Hashimoto
Cyclohelminthol X, a Hexa-substituted Spirocyclopropane from Helminthosporium velutinum yone96: Structural Elucidation, Electronic Circular Dichroism Analysis,
and Biological Properties
J. Org. Chem. 2017, 82, 5574-5582.
- Kazuaki Kusakabe, Yuna Honmura, Shota Uesugi, Akio Tonouchi, Hayato Maeda,
Ken-ichi Kimura, Hiroyuki Koshino, Masaru Hashimoto
Neomacrophorin X, a [4.4.3]Propellane-typed Meroterpenoid from Trichoderma sp. 1212-03
J. Nat. Prod. 2017, 80, 1484-1492.
- Atsushi Ito, Ikuya Kumagai, Miku Maruyama, Hayato Maeda, Akio Tonouchi,
Tatsuo Nehira, Ken-ichi Kimura, and Masaru Hashimoto
Homopetasinic acid isolated from Diaporthe sp. strain 1308-05
Tetrahedron Letters, 2016, 57, 1117-1119
- Yuna Honmura, Shota Uesugi, Hayato Maeda, Kazuaki Tanaka, Tatsuo Nehira,
Ken-ichi Kimura, Masaaki Okazaki, Masaru Hashimoto
Isolation, Absolute Structures, and Biological Properties of Cyclohelminthols I–IV from Helminthosporium velutinum yone96
Tetrahedron, 2016, 72, 1400-1405
- Miki Arayama, Shota Uesugi, Kazuaki Tanaka, Hayato Maeda, Tatsuo Nehira, Ken-ichi Kimura, Masaru Hashimoto
Homojesterones: vinylogous analogues of jesterone from Helminthosporium
velutinum TS28
Tetrahedron 2016, 72, 1031-1035.
- Miki Arayama, Hayato Maeda, Kazuaki Tanaka, Noboru Takada, Tatsuo Nehira, Masaru Hashimoto
"Achaetolide-II isolated from Helminthosporium velutinum TS28"
Tetrahedron, 2015, 71(41) 7900-7905
- Yuna Honmura, Hiroto Takekawa, Kazuaki Tanaka, Hayato Maeda, Tatsuo Nehira, Warren Hehre, and Masaru Hashimoto
Computation-Assisted Structural Elucidation of Epoxyroussoeone and Epoxyroussoedione
Isolated from Roussoella japanensis KT1651
J. Nat. Prod., 2015, 78 (7), 1505–1510
- Miki Arayama, Tatsuo Nehira, Hayato Maeda, Kazuaki Tanaka, Hisashi Miyagawa, Tamio Ueno, Seijiro Hosokawa, Masaru Hashimoto
Isolation, ECD Assisted Structural Analyses, Biosynthetic Discussions,
and Biological activities of epi-Cochlioquinones D and its Derivatives
Tetrahedron, 2015, 71, 4788-4794.
- 橋本勝
リンゴ果実上におけるマイコパラサイト現象の分子機構
有機合成化学協会誌, 73 230-240 (2015)
- Ito, A.; Maeda, H.; Tonouchi, A.; Hashimoto, M.
Relative and absolute structure of phomolide C
Biosci. Biotech. Biochem. 2015, 79(7) 1067-1069.
- Fujii, M.; Chiba, H.; Tamayama, N.; Kanamaru, S.; Hashimoto, M.
Isotopic Differentiation Protocol, a Selective Extraction of C- and N-Terminal
Ions in ESI-Ms/Ms De Novo Peptide Sequencing
Nat. Prod. Chem. Res. 2015, 3, 164.
- Hirose, A.; Kudo, S.; Murakami, T.; Tanaka, K.; Harada, K.; Hashimoto,
M.
"Lambertellin System, the mechanism for fungal replacement of Moniliniafructigena with Lambertellacorni-maris without competitive inhibition on ager media."
Bioorg. Med. Chem., 22, 2489, (2014).
- 橋本勝
「リンゴ果実におけるマイコパラサイト現象の生物有機化学的研究」
日本化学会生体機能関連部会ニュースレター、Vol. 28, No.3 (2014. 1. 23)
- Hirose, A.; Maeda, H.; Tonouchi, A.; Nehira, T.; Hashimoto, M.
Neomacrophorin I, II, and III, novel drimenyl cyclohexanes with hydroxylated
butanoates from Trichoderma sp. 1212-03
Tetrahedron, 70, 1458-1463 (2014).
- Tayone, W. C.; Tayone, J. C.; Hashimoto, M
Isolation and structure elucidation of potential anti-dengue metabolites from tawa-tawa (Euphorbia hirta Linn.)
Walailak Journal of Science and Technology , 2014, 11, 825-832..
- 橋本勝
「PlipastatinとFengucinにおける構造混乱の終結」
化学と生物、51, 840-843 (2013).
- Yasumura, R.; Ashtekar, K. D.; Tonouchi, A.; Nehira, T.; Borhan, B.; Hashimoto,
M.
7-β- and 10-β-Hydroxylated congeners of CAF-603; elucidation of absolute
configuration of CAF-603 family, and their SAR studies in the anti-fungal
activity
Tetrahedon 2013, 69, 9469-9474 (2013).
- 橋本勝
Spartanの化学シフト計算による天然物の構造決定
Wavefunction User Letter No4.(右クリックで保存してから開くことができます。)
- Takekawa, H.; Tanaka, K.; Fukushi, E.; Nehira, T.; Hashimoto, M.
Roussoellols A and B, Tetracyclic Fusicoccanes from Roussoella hysterioides
J. Nat. Prod., 76, 1047–1051 (2013).
- Takada, N.; Wakita, E.; Yamazaki, E.; Hashimoto, M.; Koda, Y. T
Methyl 3-iso-cucurbate, a potential bolting inhibitor to Brassica rapa
Tetrahedron 69, 5426–5430, (2013).
- R. Yasumura; K. Tanaka.; T. Nehira; M. Hashimoto.
Structural corrections of photinides A, B and their novel derivatives
Tetrahedron, 68, 7991-7996 (2012).
- M. Honma, K. Tanaka, K. Konno, K. Tsuge, T. Okuno, M. Hashimoto
Termination of the structural confusion between plipastatin A1 and fengycin
IX
Bioorg. Med. Chem., 20, 3793-3798 (2012).
- S. Kanamaru, M. Honma, T. Murakami, T. Tsushima, S. Kudo, K. Tanaka, K.
Nihei, T. Nehira, M. Hashimoto,
"Absolute Stereochemistry of Altersolanol A and Alterporriols"
Chirality, 24, 137–146 (2012).
- K. Yamamoto, K. Yoon, K. Ueda, M. Hashimoto, J. R. Sparrow,
"A novel bisretinoid of retina is an Adduct on Glycerophosphoetanolamine"
Investigative Ophthalmology & Visual Science, 51, 9084-9090 (2011).
- W. C. Tayone, S. Kanamaru, M. Honma, K. Tanaka, T. Nehira, M. Hashimoto
"Absolute Stereochemistry of Novel Isochromanone Derivatives from Leptosphaeria sp. KTC 727"
Biosci. Biotech. Biochem, 75, 2390-2393 (2011).
- S. Noguchi, S. Takemoto, S. Kidokoro, K.. Yamamoto, M. Hashimoto
"Syntheses of cellotriose and cellotetraose analogues as transition state
mimics for mechanistic studies of cellulases"
Bioorg. Med. Chem, 19, 3812–3830 (2011).
- N. Akiyama, S. Noguchi, M. Hashimoto
"Stereochemical differentiation in the Simmons-Smith reaction for
cyclopropanated glucopyranose derivatives as molecular probes for glycosidases"
Biosci. Biotech. Biochem, 2011, 75, 1380-1382.
-
Zaharenko, A.; Picolo, G.; Ferreira, W.; Murakami, T.; Kazuma, K.; Hashimoto, M.; Cury, Y.; de Freitas, J.; Konno, K
"Bunodosine 391: a new analgesic acylamino acid from the venom of the sea
anemone Bunodosoma cangicum"
J. Nat. Products, 74, 378–382 (2011).
-
Wilanfranco T. C.; Honma, M.; Kanamaru S.; Noguchi, S.; Tanaka, K.; Nehira,
T.; Hashimoto, M..
"Stereochemical investigations of isochromenone and isobenzofuranone isolated
from Leptosphaeria sp. KTC 727"
J. Nat. Products, 74, 425–429 (2011).
- Yamamoto, K.; Noguchi, S.; Takada, N.; Miyairi, K.; Hashimoto, M.
"Synthesis of a trigalacturonic acid analogue mimicking the expected
transition state in the glycosidases"
Crabohydr. Res. 345, 572-585, (2010).
- Honma, M.; Kudo, S.; Takada, N.; Miura, T.; Hashimoto, M.
"Novel Neofusapyrones Isolated from Verticillium dahliae as Potent Antifungal Substances"
Bioorg. Med. Chem. Lett., 20, 709-712 (2010).
-
Wilanfranco T. C.; Shindo, S.; Murakami, T.; Hashimoto, M.; Tanaka, K.; Takada, N.
"Absolute stereochemistry and conformational analysis of achaetolide isolated
from Ophiobolus sp."
Tetrahedron, 65, 7464-7467 (2009).
- T. Murakami, N. Takada, M. Hashimoto
"Biosynthetic studies of spiroleptosphol"
Bioorg. Med. Chem. Lett., 19, 1122-1125 (2009).
- T. Murakami, T. Tsushima, N. Takada, K. Tanaka, K. Nihei, T. Miura, M.
Hashimoto
"Four Analogues of Spiroleptosphol isolated from Leptosphaeria doliolum"
Bioorg. Med. Chem. 19, 492-495 (2009).
- Kudo, S., Murakami, T., Miyanishi, J., Tanaka, K., Takada, N., Hashimoto,
M.
"Isolation and absolute stereochemistry of optically active sydonic acid
from from Glonium sp. (Hysteriales, Ascomycota)"
Biosci. Biotech. Biochem, 73, 203-204 (2009).
- Murakami, T.; Takada, N.; Hehre, W.; Hashimoto, M.,
Structure and Biosynthesis of Norneolambertellin Produced by Lambertella sp.1346.
Bioorg. Med. Chem, Lett, 18, 16, 4547-4549 (2008).
- 橋本勝
"Spartan Essentialを導入して ~演習講義「コンピュータ分子設計学」への展開~"
日本化学会情報化学部会誌 26, 106-112 (2008)
- Hashimoto, M.; Tsushima, T.; Murakami, T.; Nomiya, M.; Takada, N.; Tanaka,
K.
"Spiroleptosphol isolated from Leptosphaeria doliolum"
Bioorg. Med. Chem, Lett, 18, 14, 4228-4231 (2008).
- Nomiya, M., Murakami, T., Takada, N., Okuno, T., Harada, Y., Hashimoto,
M.
"Syntheses of Lambertellols and Their Stable Analogues; Investigation of
the Real Active Species in the Mycoparasitism by Lambertella Speciese"
J. Org. Chem, 73, 5039-5047 (2008.)
- Yamamoto, K., Sato, Y., Ishimori, A., Miyairi, K., Okuno, T., Nemoto, N.,
Shimizu, H., Kidokoro, S., Hashimoto, M.
"Synthesis of D-trigalacturonic acid methylglycoside"
Biosci. Biotech. Biochem, 71, 1230-1235 (2008)
- Schuetz, A.; Murakami, T.; Takada, N.; Junker, J.; Hashimoto, M.; Griesinger,
C
"Rdc-enhanced NMR spectroscopy in structure elucidation of natural products/small molecules: Sucro-neolambertellin as a testcase"
Angew. Chem. Int. Ed. 47, 2032-2034 (2008).
- T. Murakami, N. Takada, Y. Harada, T. Okuno, M. Hashimoto,
"Stimulation of the Biosynthesis of the Antibiotics Lambertellols by the
Mycoparasitic Fungus Lambertella corni-maris under the Acidic Conditions Produced by Its Host Fungus in Vitro",
Biosci. Biotech. Biochem., 71, 1230-1235 (2007)
- Hashimoto, M., Murakami, T., Funahashi, K., Tokunaga, T., Nihei, K., Okuno,
T., Kimura, T., Naoki, H., Himeno, H.
An RNA polymerase inhibitor, cyclothiazomycin B1, and its isomer.
Bioorg. Med. Chem,, 14, 8259–8270 (2006)
- 橋本勝
ピラノース環酸素を硫黄原子で置換したチオオリゴサッカリドの合成研究, (総合論文)
有機合成化学協会誌, 64(7), 766-777, (2006).
- Yamamoto, K., Watanabe, N., Matsuda, H., Oohara, K., Araya, T., Hashimoto,
M., Miyairi, K., Okazaki, I., Saito, M., Shimizu, T., Kato, H., Okuno,
T.
Design, synthesis, and enzymatic property of a sulfur-substituted analogueof trigalacturonic acid
Bioorg. Med. Chem, Lett., 15, 22, 4932-4935 (2005).
- Murakami, T., Hashimoto, M., Okuno, T.
Isolation, structure elucidation, preparation,and biological properties
of neolambertellin
Bioorg. Med. Chem, Lett., 15, 4185-4188 (2005)
- Morii, Y., Matsuda, Y., Ohara, K., Hashimoto, M., Miyairi, K., Okuno, T.
Synthetic studies on oligosaccharides composed of 5-thioglucopyranose units
Bioorg. Med. Chem., 13, 5113-5144 (2005)
- Murakami T., Sasaki A.., Fukushi E., Kawabata J., Hashimoto M., Okuno T.
Lambertellol C, a labile and novel biosynthetic congener of lambertellols
A and B
Bioorg. Med. Chem. Lett., 15, 2587-2590 (2005).
- Murakami T., Sasaki A., Fukushi E., Kawabata J., Hashimoto M., Okuno T.
Optimization of isotope-labeling conditions for lambertellin based on isotope patterns observed by mass spectrometry
Bioorg. Med. Chem. Lett., 15, 2591-2594 (2005).
- Nihei K., YING B.-P., Murakami T., Matsuda H., Hashimoto M. & Kubo
I.
Pachyelasides A-D, Novel Molluscicidal Triterpene Saponins from
Pachyelasma Tessmannii
J. Agric. Food Chem., 53, 608-613
(2005).
- Murakami T., Takahashi Y., Fukushi E., Kawabata J., Hashimoto M., Okuno
T.& Harada Y.
Biosynthesis of Lambertellols Based on the High Specific Incorporation
of the 13C-Labeled Acetates and Their Biological Properties,
J, Am. Chem. Soc., 126, 9214-9220 (2004).
- Fujita J., Matsuda H., Yamamoto K., Morii Y., Hashimoto M., Okuno
T.& Hashimoto K.
Synthesis of thiosaccharides employing the Pummerer
rearrangement of tetrahydrothiopyran oxides,
Tetrahedron, 60,
6829-6851 (2004).
- Murakami, T., Morikawa, Y., Hashimoto, M., Okuno, T. & Harada, Y.
Lambertellols A and B, Novel 3,4-Dihydronaphthalen-1(2H)-ones with Spiro-butenolide Produced by Lambertella sp.1346.
Org. Lett.
6, 157-160 (2004).
- Matsuda, H., Fujita, J., Morii, Y., Hashimoto, M., Okuno, T. &
Hashimoto, K.
Pummerer rearrangement of 1-deoxy-5-thioglucopyranose oxides;
novel synthesis of 5-thioglucopyranose derivatives.
Tetrahedron
Lett., 44, 4089-4093 (2003).
- Matsuda, H., Ohara, K., Morii, Y., Hashimoto, M., Miyairi, K. & Okuno,
T.
α-Selective Glycosylation with 5-thioglucopyranosyl Donnors; Synthesis
of an Isomaltotetraoside mimic Composed of 5-thioglucopyranose Units.
Bioorg. Med. Chem. Lett., 13, 1063-1066 (2003).
- Hashimoto, M., Matsumoto, M., Yamada, K. & Terashima,
S. Synthetic
studies of carzinophilin. Part 4: Chemical and biological properties of
carzinophilin analogues.
Tetrahedron 59, 3089-3097
(2003).
- Hashimoto, M., Sugiura, M. & Terashima, S.
Synthetic studies of
carzinophilin. Part 3: Synthetic approach toward carzinophilin and successful
synthesis of 13-O-desacetyl-12,13-di-O-benzyl-4-O-methylcarzinophilin.
Tetrahedron 59, 3063-3087 (2003).
- Hashimoto, M., Matsumoto, M. & Terashima, S.
Synthetic studies of
carzinophilin. Part 2: Synthesis of
3,4-dibenzyloxy-2-methylidene-1-azabicyclo[3.1.0]hexane systems corresponding to
the C1-17 fragment of carzinophilin.
Tetrahedron 59, 3041-3062
(2003).
- Hashimoto, M., Matsumoto, M. & Terashima, S.
Synthetic studies of
carzinophilin. Part 1: Synthesis of 2-methylidene-1-azabicyclo[3.1.0]hexane
systems related to carzinophilin.
Tetrahedron 59, 3019-3040
(2003).
- Ohara, K., Matsuda, H., Hashimoto, M., Miyairi, K. & Okuno,
T
β-Selective Glycosylation of 5-Thioglucopyranose Derivatives: Synthesis
of β-(1-6)Linked 5'-Thioglucopyranosyl Disaccharides.
Chemistry Lett.
2002, 626-627 (2002).
- Matsuda, H., Hashimoto, M. & Okuno, T.
Novel Preparation of
(2-Azidomethyl)benzoic Acid and an Application as a Protective Group.
Syn. Commun. 32, 3347-355 (2002).
- Aoki, K., Takahashi, M., Hashimoto, M., Okuno, T., Kurata, K. & Suzuki,
M.
Total Synthesis of Both Enantiomers of Dictyochromenol and their
(Z)-Isomers.
Biosci. Biotech. Biochem. 66, 1915-1924
(2002).
- Ben-Shabat, S., Craig, P., A, Hashimoto, M., Liu, J., Koji, N. &
Sparrow, J.
Fluorescent Pigments if the Retinal Pigment Epithelium and
Age-related Macular Degeneration.
Bioorg. Med. Chem. Lett. 11,
1533-1540 (2001).
- Lin, S., Fang, K., Hashimoto, M., Nakanishi, K. & Ojima, I..
Design and Synthesis of a novel Photoaffinity Taxoid as a Potential Probe
for the Study of Paclitaxel-microtubules Interactions.
Tetrahedron Lett., 41,
4287-4290 (2000).
- Sparrow, J., Craig, P., A, Hashimoto, M. & Nakanishi, K.
A2E, a Lipofuscin Fluorophore, in Human Retinal Pigmented Epithelial Cells
in Culture.
IVOS 40, 2988-2995 (1999).
- Lou, J., Hashimoto, M., Nina, B. & Nakanishi, K.
Enantioselective
Binding of an 11-cis-Locked Cyclopropyl Retinal. The Conformation of Retinal in
Bovine Rhodopsin.
Org. Lett. 1, 51-54 (1999).
- Hashimoto, M. & Fujimoto, Y.
One Step and Convenient Preparations of
4-Hydroxyretinal and 4-Oxoretinal.
Syn. Commun. 29, 3793-3797
(1999).
- Hashimoto, M., Liu, Y., Fang, K., Li, H.-y. & Nakanishi,
K.
Preparation and Biological Properties of Biotinylated PhTX Derivatives.
Bioorg. Med. Chem. 7, 1181-1194 (1999).
- Hashimoto, M. & Terashima, S.
A Stereoselective Synthesis of
4-O-methyl-13-Desacetyl-12,13-di-O-benzylcarzinophilin.
Heterocycles
47, 59-64 (1998).
- Fang, K., Hashimoto, M., Jockusch, S., Turro, N. J. & Nakanishi, K.
A Bifunctional Photoaffinity Probe for Ligand/Receptor Interaction Studies.
J,
Am. Chem. Soc., 120, 8543–8544 (1998).
- Craig, P., A, Hashimoto, M., Nakanishi, K., Dillon, J. & Sparrow,
J.
Isolation and One-step Preparation of A2E and Iso-A2E, Fluorophores from
Human Retinal Epithelium.
Proc. Nat. Acd. Sci. USA, 95,
14609-14613 (1998).
- Yoshino, T., Nagata, Y., Itoh, E., Hashimoto, M., Katoh, T. & Terashima,
S.
Total Synthesis of an Enantiomeric Pair of Fr900482. 2. Synthesis of the
Aromatic and Optically Active Aliphatic Segments.
Tetrahedron 53,
10239-10252 (1997).
- Yoshino, T., Nagata, Y., Itoh, E., Hashimoto, M., Katoh, T. & Terashima,
S.
Total Synthesis of Natural (+)-FR-900482. 2. Efficient Synthesis of the Aromatic and Optically Active Aliphatic Fragments.
Tetrahedron Lett.,
37, 3475-3478 (1996).
- Nakajima, N., Kirihara, M., Matsumoto, M., Hashimoto, M., Katoh, T. &
Terashima, S.
One-step Synthesis of (5)-Epi-Hydantocidin.
Heterocycles 42, 503-508 (1996).
- Nakajima, N., Matsumoto, M., Kirihara, M., Hashimoto, M., Katoh, T. &
Terashima, S.
Novel Synthesis of (+)-Hydantocidin Based on the Plausible
Biosynthetic Pathway.
Tetrahedron 52, 1177-1194 (1996).
- Tamura, O., Hashimoto, M., Kobayashi, Y., Katoh, T., Nakatani, K., Kamada,
M., Hayakawa, I., Akiba, T. & Terashima, S.
Synthetic Studies on the Key
Component of the New Generation of Quinolonecarboxylic Acid, DU-6859. 2.
Asymmetric Synthesis of (1R,2S)-2-Fluorocyclopropylamine.
Tetrahedron
50, 3905-3194 (1994).
- Tamura, O., Hashimoto, M., Kobayashi, Y., Katoh, T., Nakatani, K., Kamada,
M., Hayakawa, I., Akiba, T. & Terashima, S.
Synthetic Studies on the Key
Component of the New Generation of Quinolonecarboxylic Acid, DU-6859. 1.
Synthesis of (1R,2S)-2-Fluorocyclopropylamine by the Use of Optical Resolution.
Tetrahedron 50, 3889-3904 (1994).
- Hashimoto, M. & Terashima, S.
A Novel Synthesis of the C1-C17
Fragment of Carzinophilin.
Tetrahedron Lett., 35, 9409-9412
(1994).
- Hashimoto, M. & Terashima, S.
A Stereoselective Synthesis of a Novel
Model Compound of Carzinophilin Carrying the C6-C13 Unit with Correct
Stereochemistry.
Chemistry Lett., 1101-1104 (1994).
- Hashimoto, M., Matsumoto, M., Yamada, K. & Terashima, S.
Synthesis,
Chemical Reactivity, and Cytotoxicity of Carzinophilin Congeners Carrying a
2-(Acylamino-1-alkoxycarbonyl)methylidene-1-azabicyclo[3.1.0]hexane System.
Tetrahedron Lett., 35, 2207-2210 (1994).
- Tamura, O., Hashimoto, M., Kobayashi, Y., Katoh, T., Nakatani, K., Kamada,
M., Hayakawa, I., Akiba, T. & Terashima, S.
Asymmetric Synthesis of
(1R,2S)-2-Fluorocyclopropylamine. the Key Intermediate of the New Generation of
quinolonecarboxylic acid, DU-6859.
Tetrahedron Lett., 33,
3487-3490 (1992).
- Tamura, O., Hashimoto, M., Kobayashi, Y., Katoh, T., Nakatani, K., Kamada,
M., Hayakawa, I., Akiba, T. & Terashima, S.
Synthesis and Optical
Resolution of dl-cis-2-Fluorocyclopropylamine, the Key Component of the New
Generation of Quinolonecarboxylic acid, DU-6859.
Tetrahedron Lett.,
34, 3483-3486 (1992).
- Hashimoto, M., Yamada, K. & Terashima, S.
Chemical Reactivity, and
Cytotoxicity of 2-Bis(alkoxycarbonyl)methylidene-1-azabicyclo[3.1.0]hexane
Systems Related to Antitumor Antibiotic Carzinophilin A.
Chemistry Lett.,
975-978 (1992).
- Hashimoto, M., Harigaya, H., Yanagiya, M. & Shirahama, H.
Total
Synthesis of the meso-Triterpene Polyether Teurilene.
J. Org. Chem.
56, 2299-2311 (1991).
- Hashimoto, M., Kan, T., Nozaki, K., Yanagiya, M., Shirahama, H. &
Matsumoto, T.
Total Synthesis of (+)-Thyrsiferol, (+)-Thyrsiferyl 23-Acetate,
and Teurilene.
J. Org. Chem. 55, 5088-5017 (1990).
- Hashimoto, M., Yanagiya, M., Okuno, T. & Shirahama, H.
The Absolute
Configuration of 4,6-decadiyne-1,3,8-triol Isolated from Gymnopiliun
spectabilis.
Bull. Chem. Soc. Jpn. 62, 2751-2752 (1989).
- Kan, T., Hashimoto, M., Yanagiya, M. & Shirahama, H.
Effective
Deprotection of 2-(Trimethylsilylethoxy)methylated Alcohols (SEM Ethers).
Synthesis of Thyrsiferyl-23 Acetate.
Tetrahedron Lett., 29,
5417-5418 (1988).
- Hashimoto, M., Harigaya, H., Yanagiya, M. & Shirahama, H.
A Short
Step Synthesis of Teurilene. Stereocontrolled Sequential Double Cyclization of
the C30-Tetraenetetraol to the Tandem Tetrahydrofurane System.
Tetrahedron
Lett., 29, 5947-5948 (1988).
- Hashimoto, M., Yanagiya, M. & Shirahama, H.
Total Synthesis of
meso-Triterpene Ether, Teurilene. Chemistry Lett., 645-646 (1988).
- Hashimoto, M., Kan, T., Nozaki, K., Yanagiya, M., Shirahama, H. &
Matsumoto, T.
Total Synthesis of (+)-Thyrsiferol and (+)-Venustatriol.
Tetrahedron Lett., 29, 1143-1144 (1988).
- Hashimoto, M., Kan, T., Yanagiya, M., Shirahama, H. & Matsumoto,
T.
Synthesis of A-B-C-ring Segment of Thyrsiferol: Construction of a Strained
Tetrahydropyrane Ring Existing as a Boat Form.
Tetrahedron Lett.,
28, 5665-5668 (1987).