発表論文(2024年10月現在)

 
  1. Ryuhi Kanehara, Yuki Oinuma, Hayato Maeda, Kazuaki Tanaka, Masaru Hashimoto
    Triantaspirols A–C and Paraphaeolactone Cs from Paraphaeosphaeria sp. KT4192: Sensitivity of CP3 in Distinguishing Close NMR Signals
    J. Nat. Prod. 2024, accepted
     
     
  2. 橋本勝,: 天然物の不思議な構造に魅せられて, 有機合成化学協会誌, 2024, 82, 9, 922-925.
      
  3. 橋本勝: 計算機化学を利用した有機化合物の構造決定 密度汎関数化学シフト計算の進展, 月刊化学, 2024, 79, 9, 70-71.
      
  4. Taichiro Tokizaki, Ryuhi Kanehara, Hayato Maeda, Kazuaki Tanaka, and Masaru Hashimoto
    Highly Functionalized Spirobisnaphthalenes from Roussoella sp. KT4147
    J. Nat. Prod. 2024, 87, 1798-1807.
     
     
  5. Shunta Kobayashi, Nurcahyo Iman Prakoso, Xin Zheng, Shin-ichiro Noro, Masaru Hashimoto, Tatsuya Morozumi, and Taiki Umezawa
    Synthesis and Conformational Analysis of α,β-Dichlorocarbonyl Compounds
    Eur. J. Org. Chem., 2024, 27, e202400489..
     
  6. H. Arita, R. Tanaka, S. Kikukawa, T. Tomizawa, H. Sakata, M. Funada, K. Tomiyama, M. Hashimoto, T. Tasaka, H. Tabata, K. Nakamura, K. Makino, T. Oshitari, H. Natsugari, H. Takahashi: J. Med. Chem. 2024, 67, 10447-10463.l.
    Fentanyl-Type Antagonist of the μ-Opioid Receptor: Important Role of Axial Chirality in the Active Conformation
    J. Med. Chem. 2024, 67, 10447-10463.
     
  7. K. Hashimoto, H. Maeda, M. Hashimoto,
    Stereoselective Preparation of the Tricyclic Hexa-substituted Spirocyclopropane Core of Cyclohelminthol X
    Org. Lett. 2024, 26, 5873-5876.
       
      
  8. Y. Horie, M. Uchikata, S. Ueda, G. Yamahira, M. Hashimoto, K. Sakamoto, H. Ito, S. Hamada
    In vitro synthesis of oryzamutaic acid H using recombinant L-lysineε-dehydrogenase from Agrobacterium tumefaciens
    J. Biotech. 2024, 385 , 42-48.
       
  9. Y. Oinuma, R. Kanehara, H. Maeda, T. Nishikawa, K. Konno, K. Tanaka, M Hashimoto
    Isolation of Paraphaeoketones: A Plausible Biosynthetic Explanation for Paraphaeolactones via a Benzilic Acid Rearrangement Rather than a Favorskii Rearrangement
    J. Nat. Prod. 2024, 87 (4), 1159-1170.

      
  10. K. Ujiie, C. Tanaka, M. Arai, M. Hashimoto, Y. Yoshida, T. Kawano, S. Tamura
    Proposal for Structure Revision of Pinofuranoxin A through Total Syntheses of Stereoisomers
    J. Nat.l Med, 2024, 78, 608-617.
       
  11. J. Wu, K. Uchida, A. Yoshikawa, M. Hashimoto, M. Kondo, K. Nihei, M. Ishii, J-H. Choi, Y. Miwa, C. Shoda, D. Lee, A. Nakai, T. Kurihara, C. N. D’Alessandro-Gabazza, M. Toda, T. Yasuma, E. C. Gabazza, H. Hirai, H. Kawagishi
    "Fruiting Liquid” of Mushroom-Forming Fungi, A Novel Source of Bioactive Compounds – Fruiting-Body Inducer and HIF and Axl Inhibitors
    J. Agr. Food Chem, 2023, 71, 13338-13345
        
  12. K. Hashimoto, K. Kimura, K. Ishida, E. Morita, K. Tanaka. M. Hashimoto
    HIV-1 Integrase Inhibitor, Dihydroobionin B, and the Investigation of Its Extraordinary Specific Rotation
    J. Nat. Prod. 2023, 2139–2144

     
  13. R. Kanehara, Y. Oinuma, H. Maeda, M. Okazaki, K. Konno, K. Tanaka, M. Hashimoto
    Pseudo-Enantiomeric Paraphaeolactones and Their Biosynthetic Derivatives from Paraphaeosphaeria sp. KT4192: A Proposition of a Favorskii Rearrangement for Their Biosynthesis
    J. Nat. Prod. 2023, 86, 1832-1843.

     
  14. J. Wu, Y. Kamiishi, K. Shimozaki, M. Kondo, M. Hashimoto, J. Choi, C. N D’Alessandro-Gabazza, M. Toda, T. Yasuma, E. C Gabazza, H. Hirai, H. Kawagishi
    Novel cyclopropyl compounds, cyclopropylvirgines A to G, from the fruiting bodies of Amanita virgineoides
    Bull. Chem. Soc. Jpn. 2023, 96 (6), 503-509
     
  15. R. Kanehara, K. Tanaka, T. Yamada, H. Koshino and M. Hashimoto
    Termination of the Chirality Confusion of Peribysins
    Bull. Chem. Soc. Jpn. 2023, 96 (4), 318-320 (selected paper)

      
  16. S. Miura, K. Ishida, K. Tanaka, E. Morita and M. Hashimoto
    Integrasone Derivatives Isolated from Lepteutypa sp. KT4162 and Their Anti-HIV-1 Integrase Activity
    J. Nat. Prod. 2023, 86(4), 1019-1024
     
      
  17. R. Kanehara, A. Tonouchi, K. Konno, H.i Koshino, M. Hashimoto,*
    Isolation of cyclohumulanoids from Daedaleopsis tricolor and their biosynthesis based on in silico simulations
    Tetrahedron, 2022, 92, 132251.

      
  18. Naoaki Kurisawa, Arihiro Iwasaki, Kazuya Teranuma, Shingo Dan, Chikashi Toyoshima, Masaru Hashimoto, Kiyotake Suenaga
    Structural Determination, Total Synthesis, and Biological Activity of Iezoside, a Highly Potent Ca2+-ATPase Inhibitor from the Marine Cyanobacterium Leptochromothrix valpauliae
    J. Am. Chem. Soc. 2022, 144 (24), 11019–11032.
      
  19. Ayane Hayasaka, Kazuki Hashimoto, Katsuhiro Konno, Kazuaki Tanaka, Masaru Hashimoto
    Isolation, Identification, and DFT-based Conformational Analysis of Sesquikarahanadienone and its Congeners from Freshwater Dothideomycetes Neohelicascus aquaticus KT4120
    Bull. Chem. Soc. Jpn. 2022, 95 (5), 833-845 
    BCSJ Award article
      
      
  20. Takino, Junya, Kotani, Akari, Ozaki, Taro, Peng, Wenquan, Yu, Jie, Guo, Yian, Mochizuki, Susumu, Akimitsu, Kazuya, Hashimoto, Masaru, Ye, Tao, Minami, Atsushi, Oikawa, Hideaki
    Biochemistry-Guided Prediction of the Absolute Configuration of Fungal Reduced Polyketides
    Angewandte Chemie International Edition, 2021, 60, 43, 23403-23411
     
  21. Ryuhi Kanehara, Akio Tonouchi, Katsuhiro Konno, and Masaru Hashimoto
    Cyclohumulanoid Sesquiterpenes from the Culture Broth of the Basidiomycetous Fungus Daedaleopsis tricolor
    Molecules, 2021, 26 (14), 4364..
      
      
  22. Ayane Hayasaka, Kazuaki Tanaka, and Masaru Hashimoto
    Isolation and Structural Elucidation of Novel Fusicoccan Dehydroxypericonicin A from Roussoella sp.
    Biosci. Biotech. Biochem. 2021, 85(8), 1798-1801.

       

      
  23. Ryuhi Kanehara, Ayane Hayasaka, Kota Inose, Takeshi Okamura, Satomi Miura, Kazuaki Tanaka, and Masaru Hashimoto
    Decaspirones and Palmarumycins from Phaeoseptum sp. KT4106: Chirality Reinvestigation of Palmarumycins CP4a and CP5

    Tetrahedron Lett., 2021, 92, 132251

     

  24. Osamu Ishibashi, Mami Nishiyama, Eunsang Kwon, Masaru Hashimoto, Shigefumi Kuwahara, Masaru Enomoto
    Semipinacol rearrangement of a bicyclo [7.2. 0] undecane framework into a bicyclo [6.3. 0] undecane skeleton: A model study on the biosynthesis of seiridiasteriscane A
    Biosci. Biotech. Biochem. 2021, 85(7), 1621-2627
     

  25. Inose, Kota; Tanaka, Shizuya; Tanaka, Kazuaki; Hashimoto, Masaru,
    Cyclohelminthol CPs: Scope and Limitations of Density-functional-theory-based Structural Elucidation of Natural Products
    J. Org. Chem., 2021, 86( 2), 1505-1515..

  26. Wilanfranco C Tayone, Kotaro Ishida, Simon Goto, Janeth C Tayone, Masashi Arakawa, Eiji Morita, Masaru Hashimoto
    Anti-Japanese Encephalitis Virus (JEV) Activity of Triterpenes and Flavonoids from Euphorbia hirta
    Philippine Journal of Science 149 (3), 603-613 2020
     
  27. M. Matsumoto, S. Miura, A. Tonouchi, Masaru Hashimoto*
    DFT-Supported structure determination of gymunomitr-3(15)-en-4b,9b-diol
    Tetrahedron, 2020, 76(27), 131301
     
     
  28. Wilanfranco C. Tayone, Mami Nishiyama, Kazuaki Tanaka Masaru Enomoto, and Masaru Hashimoto
    DFT Supported Structural Elucidations of Seiridiasteriscane A, Unique 15-nor-Asteriscane and Novel Pestalotiopsin Congeners from Seiridium sp. KT3957
    Tetrahedron, 2020,76, (20), 131197
     
      
  29. Mami Nishiyama, Wilanfranco C. Tayone, Hayato Maeda, Kazuaki Tanaka, Masaru Hashimoto
    DFT Supported Structural Revision of Seiricardines
    Bull. Chem. Soc. Jpn. 2020, 93(6), 768-775.
     
      

  30. Tetsuya Shiina, Taro Ozaki, Yusuke Matsu, Shota Nagamine, Chengwei Liu, Masaru Hashimoto, Atsushi Minami, Hideaki Oikawa
    Oxidative Ring Contraction by a Multifunctional Dioxygenase Generates the Core Cycloocatadiene in the Biosynthesis of Fungal Dimeric Anhydride Zopfiellin
    Org. Lett., 2020, 22 (5), 1997-2000.

  31. Uesugi S, Honmura Y, Nishiyama M, Kusakabe K, Tonouchi A, Yamashita T, Hashimoto M, Kimura K-i.
    Identification of neomacrophorins isolated from Trichoderma sp. 1212-03 as proteasome inhibitors.
    Bioorg. Med. Chem. 2019, 27, 115161.
     
  32. Mami Nishiyama, Akio Tonouchi, Hayato Maeda, and Masaru Hashimoto
    DFT calculation-assisted stereo-structural assignment of arundifungin
    Chirality, 2020, 32, 17-31
      
      
  33. 橋本勝, 福士江里, Warren Hehre
    DFT計算支援による天然物のNMR解析
    日本核磁気共鳴学会機関誌、2019, vol10, 31-41.
     
  34. Hehre, W. J.; Kuunzinger, P.; Deppmeier, B.; Driessen, A.; Uchida, N.; Hashimoto, M.; Fukushi, E.; Takata, Y.,
    An Efficient Protocol for Accurately Calculating 13C Chemical Shifts of Conformationally Flexible Natural Products: Scope, Assessment and Limitations.
    J. Nat. Prod. 2019 82, 2299-2306.
      .

      
  35. Kota Inose, Kazuaki Tanaka, Hiroyuki Koshino, Masaru Hashimoto
    Cyclopericodiol and Novel Chlorinated Melleins Isolated from Periconia macrospinosa KT3863
    Tetrahedron, 2019, 75, 130470
      
      
  36. Takahiro Ugai, Atsushi MInami, Shizuya Tanaka, Raro Ozaki, Chengwei Liu, Hideyuki Shigemori, Masaru Hashimoto, Hideaki Oikawa
    Biosynthetic machinery of 6‐hydroxymellein derivatives leading to cyclohelminthols and palmaenones
    ChemBioChem, accepted publication
      
  37. Mami Nishiyama, Hayato Maeda, Akio Tonouchi, and Masaru Hashimoto
    Neomacrophorin and Premacrophorin Congeners from Trichoderma sp. 1212-03
    Tetrahedron, 2019, 75, 2993-3000.

      
  38. Manami Matsumoto, Mami Nishiyama, Hayato Maeda, Akio Tonouchi, Katsuhiro Konno, Masaru Hashimoto
     
  39. Kota Inose, Kazuaki Tanaka, Takeshi Yamada, Hiroyuki Koshino, Masaru Hashimoto
  40. Yoshida, K.; Nagai, N.; Ichikawa, Y.; Goto, M.; Kazuma, K.; Oyama, K.-i.; Koga, K.; Hashimoto, M.; Iuchi, S.; Takaya, Y.; Kondo, T.,
    Structure of two purple pigments, catechiopyranocyanidins A and B from the seed-coat of the small red bean, Vigna angularis
    Scientific Reports 2019, 9, 1484.
       
  41. Shiina, T.; Nakagawa, K.; Fujisaki, Y.; Ozaki, T.; Liu, C.; Toyomasu, T.; Hashimoto, M.; Koshino, H.; Minami, A.; Kawaide, H.; Oikawa, H.
    Biosynthetic study of conidiation-inducing factor conidiogenone: heterologous production and cyclization mechanism of a key bifunctional diterpene synthase.
    Biosci. Biotech. Biochem. 2019, 83,  192-201.
     
  42. Maeno, M.; Sasaki, K.; Guo, M.; Hashimoto, M.; Shiro, M.; Shibata, N
    Synthesis of Chiral Nonracemic α-Difluoromethylthio Compounds with Tetrasubstituted Stereogenic Centers via a Palladium-Catalyzed Decarboxylative Asymmetric Allylic Alkylation.
    Org. Lett. 2018, 20, 7044-7048.
     
  43. 橋本勝
    リンゴ果実におけるマイコパラサイト現象の生物有機化学
    日本農薬学会誌, 2018, 43, 101-108.
     
  44. 橋本 勝
    天然物構造決定におけるDFT計算の活用
    有機合成化学協会誌 2018, 76, 842-850
     
  45. Shizuya Tanaka, Kazuaki Tanaka, Hayato Maeda, and Masaru Hashimoto
    Cyclohelminthols Y1-Y4 Metabolites Possessing Two Spirocyclopropanes in their Structure
    J. Org. Chem. 2018, 83, 5688-5697

         
       
  46. Manami Matsumoto, Shizuya Tanaka, Akio Tonouchi, and Masaru Hashimoto
    12-Deoxyroridin J and 12-Deoxyepiisororidin E from Calcarisporium arbuscular
    Tetrahedron Letters, 2018. 59, 1992-1995.
        
      
      
  47. Manami Matsumoto, Atsushi Ito, Akio Tonouchi, Masaaki Okazaki, Masaru Hashimoto
    Stereochemical Correction and Total Structure of Roridin J
    Tetrahedron, 2017, 73, 5430-5435.
         
      
  48. Shizuya Tanaka, Yuna Honmura, Shota Uesugi, Eri Fukushi, Kazuaki Tanaka, Hayato Maeda, Ken-ichi Kimura, Tatsuo Nehira, Masaru Hashimoto
    Cyclohelminthol X, a Hexa-substituted Spirocyclopropane from Helminthosporium velutinum yone96: Structural Elucidation, Electronic Circular Dichroism Analysis, and Biological Properties
    J. Org. Chem. 2017, 82, 5574-5582.

         
      
  49. Kazuaki Kusakabe, Yuna Honmura, Shota Uesugi, Akio Tonouchi, Hayato Maeda, Ken-ichi Kimura, Hiroyuki Koshino, Masaru Hashimoto
    Neomacrophorin X, a [4.4.3]Propellane-typed Meroterpenoid from Trichoderma sp. 1212-03
    J. Nat. Prod. 2017, 80, 1484-1492.

         
       
     
  50. Atsushi Ito, Ikuya Kumagai, Miku Maruyama, Hayato Maeda, Akio Tonouchi, Tatsuo Nehira, Ken-ichi Kimura, and Masaru Hashimoto
    Homopetasinic acid isolated from Diaporthe sp. strain 1308-05
    Tetrahedron Letters, 2016, 57, 1117-1119
       
       
      
  51. Yuna Honmura, Shota Uesugi, Hayato Maeda, Kazuaki Tanaka, Tatsuo Nehira, Ken-ichi Kimura, Masaaki Okazaki, Masaru Hashimoto
    Isolation, Absolute Structures, and Biological Properties of Cyclohelminthols I–IV from Helminthosporium velutinum yone96
    Tetrahedron, 2016, 72, 1400-1405
      
     
  52. Miki Arayama, Shota Uesugi, Kazuaki Tanaka, Hayato Maeda, Tatsuo Nehira, Ken-ichi Kimura, Masaru Hashimoto
    Homojesterones: vinylogous analogues of jesterone from Helminthosporium velutinum TS28
    Tetrahedron 2016, 72, 1031-1035.
       
       
      
  53. Miki Arayama, Hayato Maeda, Kazuaki Tanaka, Noboru Takada, Tatsuo Nehira, Masaru Hashimoto
    "Achaetolide-II isolated from Helminthosporium velutinum TS28"
    Tetrahedron, 2015, 71(41) 7900-7905
       
      
      
      
  54. Yuna Honmura, Hiroto Takekawa, Kazuaki Tanaka, Hayato Maeda, Tatsuo Nehira, Warren Hehre, and Masaru Hashimoto
    Computation-Assisted Structural Elucidation of Epoxyroussoeone and Epoxyroussoedione Isolated from Roussoella japanensis KT1651
    J. Nat. Prod., 2015, 78 (7), 1505–1510
       
       
     
  55. Miki Arayama, Tatsuo Nehira, Hayato Maeda, Kazuaki Tanaka, Hisashi Miyagawa, Tamio Ueno, Seijiro Hosokawa, Masaru Hashimoto
    Isolation, ECD Assisted Structural Analyses, Biosynthetic Discussions, and Biological activities of epi-Cochlioquinones D and its Derivatives
    Tetrahedron, 2015, 71, 4788-4794.
       
       
      
  56. 橋本勝
    リンゴ果実上におけるマイコパラサイト現象の分子機構
    有機合成化学協会誌, 73 230-240 (2015)
     
  57. Ito, A.; Maeda, H.; Tonouchi, A.; Hashimoto, M.
    Relative and absolute structure of phomolide C
    Biosci. Biotech. Biochem. 2015, 79(7) 1067-1069.
       
       
     
  58. Fujii, M.; Chiba, H.; Tamayama, N.; Kanamaru, S.; Hashimoto, M.
    Isotopic Differentiation Protocol, a Selective Extraction of C- and N-Terminal Ions in ESI-Ms/Ms De Novo Peptide Sequencing
    Nat. Prod. Chem. Res. 2015, 3, 164.

       
  59. Hirose, A.; Kudo, S.; Murakami, T.; Tanaka, K.; Harada, K.; Hashimoto, M.
    "Lambertellin System, the mechanism for fungal replacement of Moniliniafructigena with Lambertellacorni-maris without competitive inhibition on ager media."
    Bioorg. Med. Chem., 22, 2489, (2014).

       
       
      
  60. 橋本勝
    「リンゴ果実におけるマイコパラサイト現象の生物有機化学的研究」
    日本化学会生体機能関連部会ニュースレター、Vol. 28, No.3 (2014. 1. 23)
     
  61. Hirose, A.; Maeda, H.; Tonouchi, A.; Nehira, T.; Hashimoto, M.
    Neomacrophorin I, II, and III, novel drimenyl cyclohexanes with hydroxylated butanoates from Trichoderma sp. 1212-03
    Tetrahedron, 70, 1458-1463 (2014).

       
       
     
  62. Tayone, W. C.; Tayone, J. C.; Hashimoto, M
    Isolation and structure elucidation of potential anti-dengue metabolites from tawa-tawa (Euphorbia hirta Linn.)
    Walailak Journal of Science and Technology , 2014, 11, 825-832..
     
  63. 橋本勝
    「PlipastatinとFengucinにおける構造混乱の終結」
    化学と生物、51, 840-843 (2013).
     
  64. Yasumura, R.; Ashtekar, K. D.; Tonouchi, A.; Nehira, T.; Borhan, B.; Hashimoto, M.
    7-β- and 10-β-Hydroxylated congeners of CAF-603; elucidation of absolute configuration of CAF-603 family, and their SAR studies in the anti-fungal activity
    Tetrahedon 2013, 69, 9469-9474 (2013).
     
         
       
     
  65. 橋本勝
    Spartanの化学シフト計算による天然物の構造決定
    Wavefunction User Letter No4.(右クリックで保存してから開くことができます。)
     
  66. Takekawa, H.; Tanaka, K.; Fukushi, E.; Nehira, T.; Hashimoto, M.
    Roussoellols A and B, Tetracyclic Fusicoccanes from Roussoella hysterioides
    J. Nat. Prod., 76, 1047–1051 (2013).

       
       
     
  67. Takada, N.; Wakita, E.; Yamazaki, E.; Hashimoto, M.; Koda, Y. T
    Methyl 3-iso-cucurbate, a potential bolting inhibitor to Brassica rapa
    Tetrahedron 69, 5426–5430, (2013).
     
  68. R. Yasumura; K. Tanaka.; T. Nehira; M. Hashimoto.
    Structural corrections of photinides A, B and their novel derivatives
    Tetrahedron, 68, 7991-7996 (2012).

       
       
     
  69. M. Honma, K. Tanaka, K. Konno, K. Tsuge, T. Okuno, M. Hashimoto
    Termination of the structural confusion between plipastatin A1 and fengycin IX
    Bioorg. Med. Chem., 20, 3793-3798 (2012).

       
        
     
  70. S. Kanamaru, M. Honma, T. Murakami, T. Tsushima, S. Kudo, K. Tanaka, K. Nihei, T. Nehira, M. Hashimoto,
    "Absolute Stereochemistry of Altersolanol A and Alterporriols"
    Chirality, 24, 137–146 (2012).

       
       
      
  71. K. Yamamoto, K. Yoon, K. Ueda, M. Hashimoto, J. R. Sparrow,
    "A novel bisretinoid of retina is an Adduct on Glycerophosphoetanolamine"
    Investigative Ophthalmology & Visual Science, 51, 9084-9090 (2011).
     
  72. W. C. Tayone, S. Kanamaru, M. Honma, K. Tanaka, T. Nehira, M. Hashimoto
    "Absolute Stereochemistry of Novel Isochromanone Derivatives from Leptosphaeria sp. KTC 727"
    Biosci. Biotech. Biochem, 75, 2390-2393 (2011).
     
     
  73. S. Noguchi, S. Takemoto, S. Kidokoro, K.. Yamamoto, M. Hashimoto
    "Syntheses of cellotriose and cellotetraose analogues as transition state mimics for mechanistic studies of cellulases"
    Bioorg. Med. Chem, 19, 3812–3830 (2011).
     
     
       
  74. N. Akiyama, S. Noguchi, M. Hashimoto
    "Stereochemical differentiation in the Simmons-Smith reaction for cyclopropanated glucopyranose derivatives as molecular probes for glycosidases"
    Biosci. Biotech. Biochem, 2011, 75, 1380-1382.
     
  75. Zaharenko, A.; Picolo, G.; Ferreira, W.; Murakami, T.; Kazuma, K.; Hashimoto, M.; Cury, Y.; de Freitas, J.; Konno, K
    "Bunodosine 391: a new analgesic acylamino acid from the venom of the sea anemone Bunodosoma cangicum"

    J. Nat. Products, 74, 378–382 (2011).

      

       

  76. Wilanfranco T. C.; Honma, M.; Kanamaru S.; Noguchi, S.; Tanaka, K.; Nehira, T.; Hashimoto, M..
    "Stereochemical investigations of isochromenone and isobenzofuranone isolated from Leptosphaeria sp. KTC 727"
    J. Nat. Products, 74,
    425–429 (2011).

      

       

  77. Yamamoto, K.; Noguchi, S.; Takada, N.; Miyairi, K.; Hashimoto, M.
    "Synthesis of a trigalacturonic acid analogue mimicking the expected transition state in the glycosidases"
    Crabohydr. Res. 345, 572-585, (2010).

       

      
  78. Honma, M.; Kudo, S.; Takada, N.; Miura, T.; Hashimoto, M.
    "Novel Neofusapyrones Isolated from Verticillium dahliae as Potent Antifungal Substances"
    Bioorg. Med. Chem. Lett., 20, 709-712 (2010).

       

      
  79. Wilanfranco T. C.; Shindo, S.; Murakami, T.; Hashimoto, M.; Tanaka, K.; Takada, N.
    "Absolute stereochemistry and conformational analysis of achaetolide isolated from Ophiobolus sp."
    Tetrahedron, 65, 7464-7467 (2009).

       

  80. T. Murakami, N. Takada, M. Hashimoto
    "Biosynthetic studies of spiroleptosphol"
    Bioorg. Med. Chem. Lett., 19, 1122-1125 (2009).

       

     
  81. T. Murakami, T. Tsushima, N. Takada, K. Tanaka, K. Nihei, T. Miura, M. Hashimoto
    "Four Analogues of Spiroleptosphol isolated from Leptosphaeria doliolum"
    Bioorg. Med. Chem. 19, 492-495 (2009).

       

     
  82. Kudo, S., Murakami, T., Miyanishi, J., Tanaka, K., Takada, N., Hashimoto, M.
    "Isolation and absolute stereochemistry of optically active sydonic acid from from Glonium sp. (Hysteriales, Ascomycota)"
    Biosci. Biotech. Biochem, 73, 203-204 (2009).

  83. Murakami, T.; Takada, N.; Hehre, W.; Hashimoto, M.,
    Structure and Biosynthesis of Norneolambertellin Produced by Lambertella sp.1346.
    Bioorg. Med. Chem, Lett, 18, 16, 4547-4549 (2008).


       

     
  84. 橋本勝
    "Spartan Essentialを導入して ~演習講義「コンピュータ分子設計学」への展開~"
    日本化学会情報化学部会誌 26, 106-112 (2008)
     
  85. Hashimoto, M.; Tsushima, T.; Murakami, T.; Nomiya, M.; Takada, N.; Tanaka, K.
    "Spiroleptosphol isolated from Leptosphaeria doliolum"
    Bioorg. Med. Chem, Lett, 18, 14, 4228-4231 (2008).

       

     
  86. Nomiya, M., Murakami, T., Takada, N., Okuno, T., Harada, Y., Hashimoto, M.
    "Syntheses of Lambertellols and Their Stable Analogues; Investigation of the Real Active Species in the Mycoparasitism by Lambertella Speciese"
    J. Org. Chem, 73, 5039-5047 (2008.)

       

     
  87. Yamamoto, K., Sato, Y., Ishimori, A., Miyairi, K., Okuno, T., Nemoto, N., Shimizu, H., Kidokoro, S., Hashimoto, M.
    "Synthesis of D-trigalacturonic acid methylglycoside"
    Biosci. Biotech. Biochem, 71, 1230-1235 (2008)
     
  88. Schuetz, A.; Murakami, T.; Takada, N.; Junker, J.; Hashimoto, M.; Griesinger, C
    "Rdc-enhanced NMR spectroscopy in structure elucidation of natural products/small molecules: Sucro-neolambertellin as a testcase"
    Angew. Chem. Int. Ed. 47, 2032-2034 (2008).
     

       

  89. T. Murakami, N. Takada, Y. Harada, T. Okuno, M. Hashimoto,
    "Stimulation of the Biosynthesis of the Antibiotics Lambertellols by the Mycoparasitic Fungus Lambertella corni-maris under the Acidic Conditions Produced by Its Host Fungus in Vitro",
    Biosci. Biotech. Biochem., 71, 1230-1235 (2007)
     
  90. Hashimoto, M., Murakami, T., Funahashi, K., Tokunaga, T., Nihei, K., Okuno, T., Kimura, T., Naoki, H., Himeno, H.
    An RNA polymerase inhibitor, cyclothiazomycin B1, and its isomer.
    Bioorg. Med. Chem,, 14, 8259–8270 (2006)

       


  91. 橋本勝
    ピラノース環酸素を硫黄原子で置換したチオオリゴサッカリドの合成研究, (総合論文)
     有機合成化学協会誌, 64(7), 766-777, (2006).

  92. Yamamoto, K., Watanabe, N., Matsuda, H., Oohara, K., Araya, T., Hashimoto, M., Miyairi, K., Okazaki, I., Saito, M., Shimizu, T., Kato, H., Okuno, T.
    Design, synthesis, and enzymatic property of a sulfur-substituted analogueof trigalacturonic acid
    Bioorg. Med. Chem, Lett., 15, 22, 4932-4935 (2005).

       


  93. Murakami, T., Hashimoto, M., Okuno, T.
    Isolation, structure elucidation, preparation,and biological properties of neolambertellin
    Bioorg. Med. Chem, Lett., 15, 4185-4188 (2005)

       


  94. Morii, Y., Matsuda, Y., Ohara, K., Hashimoto, M., Miyairi, K., Okuno, T.
    Synthetic studies on oligosaccharides composed of 5-thioglucopyranose units
    Bioorg. Med. Chem., 13, 5113-5144 (2005)

       


  95. Murakami T., Sasaki A.., Fukushi E., Kawabata J., Hashimoto M., Okuno T.
    Lambertellol C, a labile and novel biosynthetic congener of lambertellols A and B
    Bioorg. Med. Chem. Lett., 15, 2587-2590 (2005).

       


  96. Murakami T., Sasaki A., Fukushi E., Kawabata J., Hashimoto M., Okuno T.
    Optimization of isotope-labeling conditions for lambertellin based on isotope patterns observed by mass spectrometry
    Bioorg. Med. Chem. Lett., 15, 2591-2594 (2005).

  97. Nihei K., YING B.-P., Murakami T., Matsuda H., Hashimoto M. & Kubo I.
    Pachyelasides A-D, Novel Molluscicidal Triterpene Saponins from Pachyelasma Tessmannii
    J. Agric. Food Chem., 53, 608-613 (2005).

  98. Murakami T., Takahashi Y., Fukushi E., Kawabata J., Hashimoto M., Okuno T.& Harada Y.
    Biosynthesis of Lambertellols Based on the High Specific Incorporation of the 13C-Labeled Acetates and Their Biological Properties,
    J, Am. Chem. Soc., 126, 9214-9220 (2004).

     
       

  99. Fujita J., Matsuda H., Yamamoto K., Morii Y., Hashimoto M., Okuno T.& Hashimoto K.
    Synthesis of thiosaccharides employing the Pummerer rearrangement of tetrahydrothiopyran oxides,
    Tetrahedron, 60, 6829-6851 (2004).

       


  100. Murakami, T., Morikawa, Y., Hashimoto, M., Okuno, T. & Harada, Y.
    Lambertellols A and B, Novel 3,4-Dihydronaphthalen-1(2H)-ones with Spiro-butenolide Produced by Lambertella sp.1346.
    Org. Lett. 6, 157-160 (2004).

  101. Matsuda, H., Fujita, J., Morii, Y., Hashimoto, M., Okuno, T. & Hashimoto, K.
    Pummerer rearrangement of 1-deoxy-5-thioglucopyranose oxides; novel synthesis of 5-thioglucopyranose derivatives.
    Tetrahedron Lett., 44, 4089-4093 (2003).

  102. Matsuda, H., Ohara, K., Morii, Y., Hashimoto, M., Miyairi, K. & Okuno, T.
    α-Selective Glycosylation with 5-thioglucopyranosyl Donnors; Synthesis of an Isomaltotetraoside mimic Composed of 5-thioglucopyranose Units.
    Bioorg. Med. Chem. Lett., 13, 1063-1066 (2003).

  103. Hashimoto, M., Matsumoto, M., Yamada, K. & Terashima,
    S. Synthetic studies of carzinophilin. Part 4: Chemical and biological properties of carzinophilin analogues.
    Tetrahedron 59, 3089-3097 (2003).

  104. Hashimoto, M., Sugiura, M. & Terashima, S.
    Synthetic studies of carzinophilin. Part 3: Synthetic approach toward carzinophilin and successful synthesis of 13-O-desacetyl-12,13-di-O-benzyl-4-O-methylcarzinophilin.
    Tetrahedron 59, 3063-3087 (2003).

  105. Hashimoto, M., Matsumoto, M. & Terashima, S.
    Synthetic studies of carzinophilin. Part 2: Synthesis of 3,4-dibenzyloxy-2-methylidene-1-azabicyclo[3.1.0]hexane systems corresponding to the C1-17 fragment of carzinophilin.
    Tetrahedron 59, 3041-3062 (2003).

  106. Hashimoto, M., Matsumoto, M. & Terashima, S.
    Synthetic studies of carzinophilin. Part 1: Synthesis of 2-methylidene-1-azabicyclo[3.1.0]hexane systems related to carzinophilin.
    Tetrahedron 59, 3019-3040 (2003).

  107. Ohara, K., Matsuda, H., Hashimoto, M., Miyairi, K. & Okuno, T
    β-Selective Glycosylation of 5-Thioglucopyranose Derivatives: Synthesis of β-(1-6)Linked 5'-Thioglucopyranosyl Disaccharides.
    Chemistry Lett. 2002, 626-627 (2002).

  108. Matsuda, H., Hashimoto, M. & Okuno, T.
    Novel Preparation of (2-Azidomethyl)benzoic Acid and an Application as a Protective Group.
    Syn. Commun. 32, 3347-355 (2002).

  109. Aoki, K., Takahashi, M., Hashimoto, M., Okuno, T., Kurata, K. & Suzuki, M.
    Total Synthesis of Both Enantiomers of Dictyochromenol and their (Z)-Isomers.
    Biosci. Biotech. Biochem. 66, 1915-1924 (2002).

  110. Ben-Shabat, S., Craig, P., A, Hashimoto, M., Liu, J., Koji, N. & Sparrow, J.
    Fluorescent Pigments if the Retinal Pigment Epithelium and Age-related Macular Degeneration.
    Bioorg. Med. Chem. Lett. 11, 1533-1540 (2001).

  111. Lin, S., Fang, K., Hashimoto, M., Nakanishi, K. & Ojima, I..
    Design and Synthesis of a novel Photoaffinity Taxoid as a Potential Probe for the Study of Paclitaxel-microtubules Interactions.
    Tetrahedron Lett., 41, 4287-4290 (2000).

  112. Sparrow, J., Craig, P., A, Hashimoto, M. & Nakanishi, K.
    A2E, a Lipofuscin Fluorophore, in Human Retinal Pigmented Epithelial Cells in Culture.
    IVOS 40, 2988-2995 (1999).

  113. Lou, J., Hashimoto, M., Nina, B. & Nakanishi, K.
    Enantioselective Binding of an 11-cis-Locked Cyclopropyl Retinal. The Conformation of Retinal in Bovine Rhodopsin.
    Org. Lett. 1, 51-54 (1999).

  114. Hashimoto, M. & Fujimoto, Y.
    One Step and Convenient Preparations of 4-Hydroxyretinal and 4-Oxoretinal.
    Syn. Commun. 29, 3793-3797 (1999).

  115. Hashimoto, M., Liu, Y., Fang, K., Li, H.-y. & Nakanishi, K.
    Preparation and Biological Properties of Biotinylated PhTX Derivatives.
    Bioorg. Med. Chem. 7, 1181-1194 (1999).

  116. Hashimoto, M. & Terashima, S.
    A Stereoselective Synthesis of 4-O-methyl-13-Desacetyl-12,13-di-O-benzylcarzinophilin.
    Heterocycles 47, 59-64 (1998).

  117. Fang, K., Hashimoto, M., Jockusch, S., Turro, N. J. & Nakanishi, K.
    A Bifunctional Photoaffinity Probe for Ligand/Receptor Interaction Studies.
    J, Am. Chem. Soc., 120, 8543–8544 (1998).

  118. Craig, P., A, Hashimoto, M., Nakanishi, K., Dillon, J. & Sparrow, J.
    Isolation and One-step Preparation of A2E and Iso-A2E, Fluorophores from Human Retinal Epithelium.
    Proc. Nat. Acd. Sci. USA, 95, 14609-14613 (1998).

  119. Yoshino, T., Nagata, Y., Itoh, E., Hashimoto, M., Katoh, T. & Terashima, S.
    Total Synthesis of an Enantiomeric Pair of Fr900482. 2. Synthesis of the Aromatic and Optically Active Aliphatic Segments.
    Tetrahedron 53, 10239-10252 (1997).

  120. Yoshino, T., Nagata, Y., Itoh, E., Hashimoto, M., Katoh, T. & Terashima, S.
    Total Synthesis of Natural (+)-FR-900482. 2. Efficient Synthesis of the Aromatic and Optically Active Aliphatic Fragments.
    Tetrahedron Lett., 37, 3475-3478 (1996).

  121. Nakajima, N., Kirihara, M., Matsumoto, M., Hashimoto, M., Katoh, T. & Terashima, S.
    One-step Synthesis of (5)-Epi-Hydantocidin.
    Heterocycles 42, 503-508 (1996).

  122. Nakajima, N., Matsumoto, M., Kirihara, M., Hashimoto, M., Katoh, T. & Terashima, S.
    Novel Synthesis of (+)-Hydantocidin Based on the Plausible Biosynthetic Pathway.
    Tetrahedron
    52, 1177-1194 (1996).

  123. Tamura, O., Hashimoto, M., Kobayashi, Y., Katoh, T., Nakatani, K., Kamada, M., Hayakawa, I., Akiba, T. & Terashima, S.
    Synthetic Studies on the Key Component of the New Generation of Quinolonecarboxylic Acid, DU-6859. 2. Asymmetric Synthesis of (1R,2S)-2-Fluorocyclopropylamine.
    Tetrahedron 50, 3905-3194 (1994).

  124. Tamura, O., Hashimoto, M., Kobayashi, Y., Katoh, T., Nakatani, K., Kamada, M., Hayakawa, I., Akiba, T. & Terashima, S.
    Synthetic Studies on the Key Component of the New Generation of Quinolonecarboxylic Acid, DU-6859. 1. Synthesis of (1R,2S)-2-Fluorocyclopropylamine by the Use of Optical Resolution.
    Tetrahedron 50, 3889-3904 (1994).

  125. Hashimoto, M. & Terashima, S.
    A Novel Synthesis of the C1-C17 Fragment of Carzinophilin.
    Tetrahedron Lett., 35, 9409-9412 (1994).

  126. Hashimoto, M. & Terashima, S.
    A Stereoselective Synthesis of a Novel Model Compound of Carzinophilin Carrying the C6-C13 Unit with Correct Stereochemistry.
    Chemistry Lett., 1101-1104 (1994).

  127. Hashimoto, M., Matsumoto, M., Yamada, K. & Terashima, S.
    Synthesis, Chemical Reactivity, and Cytotoxicity of Carzinophilin Congeners Carrying a 2-(Acylamino-1-alkoxycarbonyl)methylidene-1-azabicyclo[3.1.0]hexane System.
    Tetrahedron Lett., 35, 2207-2210 (1994).

  128. Tamura, O., Hashimoto, M., Kobayashi, Y., Katoh, T., Nakatani, K., Kamada, M., Hayakawa, I., Akiba, T. & Terashima, S.
    Asymmetric Synthesis of (1R,2S)-2-Fluorocyclopropylamine. the Key Intermediate of the New Generation of quinolonecarboxylic acid, DU-6859.
    Tetrahedron Lett., 33, 3487-3490 (1992).

  129. Tamura, O., Hashimoto, M., Kobayashi, Y., Katoh, T., Nakatani, K., Kamada, M., Hayakawa, I., Akiba, T. & Terashima, S.
    Synthesis and Optical Resolution of dl-cis-2-Fluorocyclopropylamine, the Key Component of the New Generation of Quinolonecarboxylic acid, DU-6859.
    Tetrahedron Lett., 34, 3483-3486 (1992).

  130. Hashimoto, M., Yamada, K. & Terashima, S.
    Chemical Reactivity, and Cytotoxicity of 2-Bis(alkoxycarbonyl)methylidene-1-azabicyclo[3.1.0]hexane Systems Related to Antitumor Antibiotic Carzinophilin A.
    Chemistry Lett., 975-978 (1992).

  131. Hashimoto, M., Harigaya, H., Yanagiya, M. & Shirahama, H.
    Total Synthesis of the meso-Triterpene Polyether Teurilene.
    J. Org. Chem. 56, 2299-2311 (1991).

  132. Hashimoto, M., Kan, T., Nozaki, K., Yanagiya, M., Shirahama, H. & Matsumoto, T.
    Total Synthesis of (+)-Thyrsiferol, (+)-Thyrsiferyl 23-Acetate, and Teurilene.
    J. Org. Chem. 55, 5088-5017 (1990).

  133. Hashimoto, M., Yanagiya, M., Okuno, T. & Shirahama, H.
    The Absolute Configuration of 4,6-decadiyne-1,3,8-triol Isolated from Gymnopiliun spectabilis.
    Bull. Chem. Soc. Jpn. 62, 2751-2752 (1989).

  134. Kan, T., Hashimoto, M., Yanagiya, M. & Shirahama, H.
    Effective Deprotection of 2-(Trimethylsilylethoxy)methylated Alcohols (SEM Ethers). Synthesis of Thyrsiferyl-23 Acetate.
    Tetrahedron Lett., 29, 5417-5418 (1988).

  135. Hashimoto, M., Harigaya, H., Yanagiya, M. & Shirahama, H.
    A Short Step Synthesis of Teurilene. Stereocontrolled Sequential Double Cyclization of the C30-Tetraenetetraol to the Tandem Tetrahydrofurane System.
    Tetrahedron Lett., 29, 5947-5948 (1988).

  136. Hashimoto, M., Yanagiya, M. & Shirahama, H.
    Total Synthesis of meso-Triterpene Ether, Teurilene. Chemistry Lett., 645-646 (1988).

  137. Hashimoto, M., Kan, T., Nozaki, K., Yanagiya, M., Shirahama, H. & Matsumoto, T.
    Total Synthesis of (+)-Thyrsiferol and (+)-Venustatriol.
    Tetrahedron Lett., 29, 1143-1144 (1988).

  138. Hashimoto, M., Kan, T., Yanagiya, M., Shirahama, H. & Matsumoto, T.
    Synthesis of A-B-C-ring Segment of Thyrsiferol: Construction of a Strained Tetrahydropyrane Ring Existing as a Boat Form.
    Tetrahedron Lett., 28, 5665-5668 (1987).



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